The World Health Organization (WHO) has released a report emphasizing the urgent need for enhanced investment in addressing noncommunicable diseases (NCDs) and mental health conditions. Titled “Saving lives, spending less,” the report highlights that an additional investment of just US$3 per person annually could result in economic benefits exceeding US$1 trillion by 2030. This call to action follows an analysis revealing a significant slowdown in progress across various regions in reducing NCD mortality rates from 2010 to 2019.
According to WHO, while 82% of countries reported reductions in NCD-related deaths during the nine-year period, many have seen a resurgence in mortality rates. NCDs, which include cardiovascular diseases, cancers, and chronic respiratory conditions, are responsible for a large portion of global deaths. Furthermore, over one billion individuals live with mental health conditions, with nearly 75% of deaths related to these issues occurring in low- and middle-income countries. This accounts for approximately 32 million lives lost each year.
Global Leaders to Address NCDs and Mental Health
On September 25, 2025, Heads of State and Government will gather in New York for the Fourth United Nations General Assembly High-Level Meeting (HLM4) focused on the prevention and control of NCDs. The meeting’s objective is to adopt a comprehensive Political Declaration aimed at accelerating global action and investment in health and development areas.
Dr. Tedros Adhanom Ghebreyesus, the WHO Director-General, stated, “Noncommunicable diseases and mental health conditions are silent killers, robbing us of lives and innovation.” He underscored the importance of investing in strategies to combat these health issues, noting that countries like Denmark, South Korea, and Moldova are setting positive examples, while others lag behind.
NCDs encompass various conditions, including heart attacks, strokes, diabetes, and certain cancers. Mental health disorders such as anxiety and depression are widespread and affect individuals across all demographics. Without immediate and sustained intervention, millions more individuals are at risk of premature death.
Cost-effective Solutions and Challenges Ahead
Despite progress in many regions, 60% of countries experienced a slowdown in reducing NCD mortality compared to the previous decade. Countries like Denmark showed the most significant improvements, while nations including China, Egypt, Nigeria, Russia, and Brazil also reported declines in mortality rates.
The largest gains were attributed to decreases in cardiovascular disease and specific cancers. However, the rising mortality rates from pancreatic and liver cancers, along with neurological conditions, present ongoing challenges.
WHO emphasizes that solutions to address NCDs and promote mental health are both affordable and effective. Governments frequently encounter lobbying from powerful industries that produce harmful products, including tobacco and ultra-processed foods. Dr. Etienne Krug, Director of WHO’s Department of Health Determinants, Promotion and Prevention, remarked, “It is unacceptable that commercial interests are profiting from increasing deaths and disease.” He urged governments to prioritize public health over corporate profits.
Implementing WHO’s ‘Best Buys’—a set of impactful interventions—could cost an additional US$3 per person per year. The potential return on this investment is substantial, with estimates suggesting it could save 12 million lives, prevent 28 million heart attacks and strokes, and contribute to over US$1 trillion in economic benefits by 2030.
The upcoming HLM4 presents a critical opportunity for global leaders to commit to transformative changes in public health. With an actionable Political Declaration, governments can reaffirm their dedication to achieving the 2030 health targets, setting a visionary course for future generations.
Dr. Devora Kestel, Director of WHO’s Department for NCDs and Mental Health, emphasized the urgency of decisive action. “We know what works. The time to act is now. Governments that act decisively will protect and save lives, cut costs, and unlock growth.”
WHO is calling on leaders, partners, and communities to advocate for concrete actions that will be essential for advancing global health initiatives and ensuring a healthier future for all.
