UPDATE: A groundbreaking study published on October 24, 2023, in the journal Current Biology, has identified the pathogens responsible for the staggering loss of Napoleon Bonaparte’s army during their infamous retreat from Russia in 1812. This urgent revelation, based on ancient DNA analysis, overturns long-held beliefs about the causes of the army’s demise.
In the summer of 1812, approximately 500,000 soldiers began the campaign against the Russian Empire, but by December, only a fraction survived. Historical accounts pointed to starvation, brutal cold, and typhus as primary culprits. However, a team of microbial paleogenomicists from the Institut Pasteur in Paris extracted DNA from the teeth of soldiers buried in a mass grave in Vilnius, Lithuania, challenging the conventional narrative.
The researchers, led by Nicolás Rascovan, discovered no trace of typhus. Instead, they identified two dangerous pathogens: Salmonella enterica, which causes enteric fever, and Borrelia recurrentis, linked to relapsing fever. These findings indicate that diseases transmitted by body lice significantly contributed to the catastrophic death toll.
“It’s very exciting to use a technology we have today to detect and diagnose something that was buried for 200 years,” Rascovan stated. This innovative approach marks a significant leap in understanding historical epidemics, as researchers utilized advanced DNA sequencing techniques to isolate and identify ancient pathogens.
Previously, studies suggested typhus was the leading cause of death due to the presence of body lice and the bacterium Rickettsia prowazekii. However, Rascovan’s team found no evidence of this pathogen, which could be attributed to the limitations of older methods like polymerase chain reaction (PCR). Their modern technique captures a broader range of DNA sources, revealing a clearer picture of the historical health crisis.
To the researchers’ astonishment, the strain of B. recurrentis found in the soldiers shares a lineage with strains uncovered in ancient Britain, dating back 2,000 years to the Iron Age. This discovery highlights the persistence of certain pathogens in Europe over millennia, showcasing the potential of ancient DNA technology to illuminate the history of infectious diseases.
The implications of this study resonate far beyond historical interest. Understanding the dynamics of past epidemics can inform current public health strategies and improve our response to modern disease outbreaks. As historians and scientists continue to unravel the mysteries of the past, this research represents a pivotal moment in the intersection of history and science.
As the world watches these developments, it’s crucial to consider how ancient events shape our understanding of health crises today. The findings from Napoleon’s retreat not only enhance our historical knowledge but also remind us of the enduring impact of infectious diseases on human history.
Stay tuned for more updates as researchers continue to explore the implications of this significant discovery.


































